Plasma Generation Chip - Four round membranes Fluidic 200

The Plasma Generation Chip - Four round membranes Fluidic 200 is a plasma separation tool designed for precise and convenient blood plasma generation. With a total plasma yield of 12-15 µl per round membrane from just 25 µl of full blood, this chip allows for accurate plasma volume extraction. Users can select the volume by using individual channels with four independent, round-shaped membranes. Its four-channel configuration maximizes throughput for sample preparation workflows in research or diagnostics.

General

This plasma generation chip has Luer and Mini Luer interfaces and features four round membranes and a venting channel. Fluidic 200 features an additional membrane venting channel to allow for an easier filling of the membrane chamber. Each round membrane (10 mm diameter) generates 12-15 µl plasma from 25 µl of full blood. Check out the sample preparation starter kit for plasma generation to get a complete set-up enabling you to start with your experiments right away!

This chip displays four independent units composed of a round plasma generation membrane to obtain plasma/serum from whole blood. Each membrane has a diameter of 10 mm and can generate roughly 12-15 µL of plasma/serum out of 25 µL full blood.

Each unit consists of a Luer interface (1) for blood loading, a support channel with a cross-section of 300 µm x 100 µm (2) for the transfer of the blood on top of a separation membrane (3), fused into a chamber of 10 mm diameter. A collection channel (4) allows to collection of the plasma/serum from below the membrane.

The unit also features a ventilation channel of 100 µm x 100 µm (5) below the membrane. The vacuum is applied via the collection channel and the related Mini Luer interface (6) to the outer world. A third interface (7), which is closed during the sample loading, helps to smoothly release the vacuum if the membrane pores are blocked by the solid components of the blood such as erythrocytes, monocytes, platelets, or leucocytes. There is also an additional venting line on the unit design for easier filling of the membrane chamber. Sample loading can be done either by pipette or via a tank and filtration can be operated passively or through a pump. 

• Luer and Mini Luer connections molded with the chip: leak-free
• Highly-resistant and optically clear material: Topas (COC)
• Standard microscope glass slide size

Features & Benefits

• High efficiency membrane plasma separation: Each membrane yields 12-15 µl plasma from a small blood input. This supports high efficiency in sample preparation work.
• Flexible volume selection: Four independent membrane chambers allow selection of plasma volumes by using individual channels.
• Simple interface options: Supports both Luer and Mini Luer connections, making device integration easy in standard laboratory setups.
• Improved filling process: Dedicated membrane venting channel allows easier and more reliable filling of the membrane chamber.
• Transparent chip body: Allows direct visual control during operation. Improves confidence in results.

This chip is designed for researchers needing reliable blood plasma extraction. The four round membranes work independently, assisting multi-sample workflows or higher sample throughput. The transparent design is suitable for applications that require quality control and process monitoring.
The robust Luer and Mini Luer interfaces make the chip compatible with many laboratory instruments. With optional surface treatments and material choices, users can pick the best fit for their application: either standard or hydrophilized surfaces, and PS or Topas chip bodies.

Applications

This plasma generation chip is ideal for sample preparation before analysis. It fits in applications where small, precise plasma volumes are needed from whole blood.

• Biomedical research
• Diagnostic sample processing
• Pharmaceutical laboratory sample preparation

Content

1x Plasma Generation Chip - Four round membranes Fluidic 200

Specifications

Documentation

Click to read more information about ChipShop chips material properties.

Check this video to see how plasma generation chips can be used. 

? Plasma generation chip 4 round membranes Fluidic 200 datasheet