PDMS chip with 3 straight channels for a wide range of applications including shear effects study, cell/particle adhesion or interactions.
Available with different channel sizes.
General
This PDMS chip with a 3-channel simplified design of different widths allows you to study shear effects according to channel size and flow rates. Assess biological processes such as cell/particle adhesion and cell/cell or cell/particle interactions at the micro-circulation scale in a very simple way.
4 variations of the width of the channels are available:
- 100 / 100 / 100 µm
- 250 / 250 / 250 µm
- 500 / 500 / 500 µm
- 100 / 250 / 500 µm
Depth of 100 µm, punched holes for 1/16" (1.6 mm) OD tubing. Standard microscope slide (75 x 25 mm).
The simplicity of the design will allow you to save up to 90% in consumables compared to conventional flow chambers.
Content
3x PDMS chip with linear channels
Specifications
| Chip material |
PDMS |
| Glass slide dimensions |
75 mm x 25 mm |
| Channels width |
100 / 100 / 100 µm
250 / 250 / 250 µm
500 / 500 / 500 µm
100 / 250 / 500 µm
|
| Channel height |
100 µm |
| Inlet/outlet size |
For 1.6 mm (1/16") OD tubing |
Documentation
Yoshida, S., & Itakura, K. (2020). Compressed holographic particle tracking velocimetry for microflow measurements. Optical Review, 27(5), 441-446. https://doi.org/10.1007/s10043-020-00616-6
Jarvis, M., Arnold, M., Ott, J., Krishnan, V., Pant, K., Prabhakarpandian, B., & Mitragotri, S. (2018). Detachment of ligands from nanoparticle surface under flow and endothelial cell contact: Assessment using microfluidic devices. Bioengineering & translational medicine, 3(2), 148-155. https://doi.org/10.1002/btm2.10089
Nowak, M., Brown, T. D., Graham, A., Helgeson, M. E., & Mitragotri, S. (2020). Size, shape, and flexibility influence nanoparticle transport across brain endothelium under flow. Bioengineering & translational medicine, 5(2), e10153. https://doi.org/10.1002/btm2.10153
