The NANOSTACKS platform is a groundbreaking system that simplifies the creation of complex in vitro models, enabling both cell-cell and organ-organ interactions. Designed to be compatible with standard 24-well plates, this platform is a versatile solution for a range of applications, including imaging-based assays and downstream sampling for ELISA and PCR.
The kit contains up to 72 insets, allowing for a combination of up to four cell types in a single well. Available with membrane pore size from 0.1 to 8 µm.
General
The NANOSTACKS Platform is a groundbreaking system that simplifies the creation of complex in vitro models, enabling both cell-cell and organ-organ interactions. Designed to be compatible with standard lab equipment, this platform is a versatile solution for a range of applications, including imaging-based assays and downstream sampling for ELISA and PCR. It's a cost-effective alternative to traditional microfluidic chips.
A new way to culture an Organ-on-a-chip
The NANOSTACKS Platform provides a modular and scalable approach to the Organ-on-a-chip concept. While traditional microfluidic chips can be rigid and expensive, NANOSTACKS uses a series of stackable plates to create 3D organoids and multi-tissue systems that mimic the complexity and interaction of human organs. This modularity allows researchers to build and customize their models without the constraints of a fixed-channel microfluidic device, making advanced organ-on-a-chip research more accessible.
Key Features & Benefits
- ✅ Versatile 3D Assembly: Effortlessly create intricate 3D models for advanced research, directly supporting the organoid component of Organ-on-a-chip.
- ✅ Enhanced Intercellular Communication: Facilitates natural cell-cell and organ-organ interactions, crucial for mimicking biological function.
- ✅ Industry-Compliant Format: Based on a standard 24-well plate, ensuring compatibility with your existing lab equipment.
- ✅ Ease of Imaging: The transparent design allows for simple, high-quality imaging without specialized equipment.
- ✅ Cost-Effective: A more affordable option compared to traditional microfluidic chips.
Content
3, 24, or 72x NANOSTACKS insets (dry)
Specifications
| Material |
Transparent PET or PC |
| Membrane Poze Size |
Standard 0.4 µm
Also available with 0.1 µm, 0.2 µm, 1 µm, 3 µm, 5µm, and 8 µm |
| Compatible Plate |
SBS-standard 24-well plate |
| Working Volume |
0.5 - 1.5 mL |
| Stackability |
Yes, up to 4 per well |
| Cell growth area |
0.28 cm² per level |
Documentation
NANOSTACKS Protocol
Application Note 1: Modeling the liver-brain axis using NANOSTACKS
Application Note 2: Development of an in vitro model of the human brain using NANOSTACKS
Application Note 3: Integrating NANOSTACKS with microelectrode array plates for AI-powered seizure liability screening
Article: Talari et al. Multicellular hepatic in vitro models using NANOSTACKSTM: human-relevant models for drug response prediction. In Vitro Model. 2025 Jun 18;4(2):131-144.
