Cross-Flow Membrane Chip - Gravitiy-driven flow option Fluidic 694

The Cross-Flow Membrane Chip - Gravitiy-driven flow option Fluidic 694 is a versatile microfluidic platform designed to enable interaction between two independent chambers via a permeable membrane. Its chamber design, volume flexibility, and multiple inlet/outlet channels support a wide range of cell culture and filtration workflows. Volume is defined by the chamber dimensions, and user can select between different membrane pore sizes (3 µm or 8 µm). The device features two independent channels, each with two inlets and one outlet per chamber, allowing for complex flow schemes and precise experimentation.

General

The cross-flow membrane chip Fluidic 694 features two independent chambers, which interact through a permeable membrane. Each chamber features two connected inlets and one outlet. The channels connecting the inlets with the chambers meander to allow for e.g. media heating. The chip is available with different membrane types, differing e.g. in pore size. Fluidic 480 can be used e.g. for cell culture experiments, where cells, such as epithelial cells are co-cultured. The chip is also ideal for applications like filtering, size exclusion, or migration studies.

Features & Benefits

• Dual-Chamber Design: Two separate chambers allow experiments where chamber-to-chamber interactions are key, such as cell co-culture or migration.
• Flexible Membrane Options: Available with 3 µm or 8 µm PET permeable membranes for tailored filtration, separation, or migration studies.
• Multiple Inlets/Outlets: Each chamber is equipped with two inlets and one outlet, expanding possibilities for solution exchange or stepwise introductions.
• Compatible Materials: Select between PS or Topas materials to suit specific chemical or optical requirements.
• Mini Luer Connectivity: Standardized mini Luer interfaces simplify system integration and handling.

The cross-flow membrane chip Fluidic 694 is designed for advanced biological and chemical workflows. The two fully separated chambers can communicate through the permeable membrane only, ensuring strict compartmentalization and reproducible experiments. The meandering channels efficiently link each inlet to its chamber, enabling temperature control or gradient generation as required. Different membrane pore sizes and surface treatments are available, offering flexibility to suit experimental demand.

This chip provides a reliable platform for applications such as cell co-culture or migration studies and can be tailored for specific sample separation or selective filtration tasks. Material and treatment options ensure compatibility with a wide range of media and enable adaptation to the needs of various research settings.

Applications

This product is primarily used in advanced laboratory and research settings. Its structure is suitable for studies that require compartmentalized interaction, filtration, or selective migration.

• Cell co-culture studies
• Molecular migration or barrier function experiments
• Selective filtration and size exclusion assays
• Media heating and gradient generation
• Basic perfusion studies

Content

1x Cross-Flow Membrane Chip - Gravitiy-driven flow option Fluidic 694

Specifications

Documentation

Cross-Flow Membrane Chip - Gravitiy-driven flow option Fluidic 694 datasheet

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Check the chemical compatibilities for this product here:
Polystyrene - Chemical Compatibility Chart
Topas - Chemical Compatibility Chart